The DYNAMO consortium is a highly competitive, cross-disciplinary team with minimal overlap, covering all main aspects in nanopore based single molecule. This forms a cohesive team, fully committed to educate the next generation of scientists, that will lead the field of plasmonic hybrid nanopore science. Our carefully selected team is at the forefront of their fields and has teaching experience. To translate societal needs to R&D, our consortium includes leading academic and industrial parties, with all relevant cutting-edge technologies in the field of inorganic nanopore, plasmonic nanostructures, and optical tweezer fabrication (Italian Institute of Technology - IIT, CICGUNE - San Sebastian Spain, CNRS - Marsille) with advanced biochemistry to design and functionalize biomolecules (University of Leipzig - Germany, University of Cambridge - UK) and to control their dynamics by DNA-origami. For the investigation of the properties of such highly complex materials, DYNAMO provides the leading expertise in SERS (University of Berlin), magneto-optics (CNRS), plasmonics (IIT, CNRS), structural characterization by electron microscopies, and singe molecule fluorescence (CNRS, TU DELFT). Important to be stressed, the different tasks attributed to the JRs/beneficiary partners are fully coherent with the expertise within the network. In particular, IIT will focus on nanofabrication, CICGUNE and CNRS on plasmonic and magneto-plasmonic trapping, University of Berlin on SERS spectroscopy, TUDELFT on fluorescence, Cambridge and University of Leipzig on combined methods to integrate DNA origami in nanopore single-molecule detectors and University Milano Bicocca on the fundamental aspects of single molecule spectroscopies. Finally, Elements s.r.l will give the network a strong connection with a final exploitation of the technology under development.